Sat 4:30p · O/U 49 (close) · Implied SF 21.5, ARI 27.5 · Roof closed
State Farm Stadium · Roof closed · Grass
Data coverageStats through Super BowlUpdating on schedule: No lines yetUpdating on schedule: Kalshi 1 min agoView sources49ers 21–18 straight up · 20–18–1 against the spread · overs 19–20 · 39 meetings
| Nov 5, 2017 W9 | @ SF | SF 10–20 | +2.5 ✗ | 30 Under 39 |
| Oct 1, 2017 W4 | @ ARI | SF 15–18 | +6.5 ✓ | 33 Under 43 |
| Nov 13, 2016 W10 | @ ARI | SF 20–23 | +14 ✓ | 43 Under 46.5 |
| Oct 6, 2016 W5 | @ SF | SF 21–33 | +3.5 ✗ | 54 Over 42.5 |
| Nov 29, 2015 W12 | @ SF | SF 13–19 | +7.5 ✓ | 32 Under 45 |
| Sep 27, 2015 W3 | @ ARI | SF 7–47 | +7 ✗ | 54 Over 45 |
| Dec 28, 2014 W17 | @ SF | SF 20–17 | −6 ✗ | 37 Under 38 |
| Sep 21, 2014 W3 | @ ARI | SF 14–23 | −3 ✗ | 37 Under 41 |
| Dec 29, 2013 W17 | @ ARI | SF 23–20 | +3 ✓ | 43 Over 41 |
| Oct 13, 2013 W6 | @ SF | SF 32–20 | −10 ✓ | 52 Over 40.5 |
| Dec 30, 2012 W17 | @ SF | SF 27–13 | −16 ✗ | 40 Over 39 |
| Oct 29, 2012 W8 | @ ARI | SF 24–3 | −7 ✓ | 27 Under 37.5 |
| Dec 11, 2011 W14 | @ ARI | SF 19–21 | −3.5 ✗ | 40 Over 39 |
| Nov 20, 2011 W11 | @ SF | SF 23–7 | −10 ✓ | 30 Under 40.5 |
| Jan 2, 2011 W17 | @ SF | SF 38–7 | −6 ✓ | 45 Over 39.5 |
| Nov 29, 2010 W12 | @ ARI | SF 27–6 | −1 ✓ | 33 Under 41.5 |
| Dec 14, 2009 W14 | @ SF | SF 24–9 | +4 ✓ | 33 Under 44.5 |
| Sep 13, 2009 W1 | @ ARI | SF 20–16 | +5 ✓ | 36 Under 45.5 |
| Nov 10, 2008 W10 | @ ARI | SF 24–29 | +9.5 ✓ | 53 Over 47.5 |
| Sep 7, 2008 W1 | @ SF | SF 13–23 | +2.5 ✗ | 36 Under 42 |
| Nov 25, 2007 W12 | @ ARI | SF 37–31 | +10 ✓ | 68 Over 37.5 |
| Sep 10, 2007 W1 | @ SF | SF 20–17 | −3.5 ✗ | 37 Under 47 |
| Dec 24, 2006 W16 | @ SF | SF 20–26 | −3.5 ✗ | 46 Over 45 |
| Sep 10, 2006 W1 | @ ARI | SF 27–34 | +9.5 ✓ | 61 Over 44 |
| Dec 4, 2005 W13 | @ SF | SF 10–17 | +3 ✗ | 27 Under 43.5 |
| Oct 2, 2005 W4 | Neutral | SF 14–31 | +3 ✗ | 45 Over 42 |
| Dec 12, 2004 W14 | @ ARI | SF 31–28 | +7 ✓ | 59 Over 36 |
| Oct 10, 2004 W5 | @ SF | SF 31–28 | −1 ✓ | 59 Over 36.5 |
| Dec 7, 2003 W14 | @ SF | SF 50–14 | −10.5 ✓ | 64 Over 40.5 |
| Oct 26, 2003 W8 | @ ARI | SF 13–16 | −7 ✗ | 29 Under 41 |
| Dec 21, 2002 W16 | @ ARI | SF 17–14 | −3.5 ✗ | 31 Under 41 |
| Oct 27, 2002 W8 | @ SF | SF 38–28 | −8.5 ✓ | 66 Over 40.5 |
| Oct 1, 2000 W5 | @ SF | SF 27–20 | −3.5 ✓ | 47 Under 47.5 |
| Sep 27, 1999 W3 | @ ARI | SF 24–10 | −2.5 ✓ | 34 Under 45.5 |