Sun 1:00p · O/U 49.5 (close) · Implied SF 21.8, NO 27.8 · Dome
Mercedes-Benz Superdome · Dome · Turf
Data coverageStats through Super BowlUpdating on schedule: No lines yetUpdating on schedule: Kalshi 1 min agoView sources49ers 5–10 straight up · 6–9 against the spread · overs 9–6 · 15 meetings
| Oct 28, 2007 W8 | @ SF | SF 10–31 | +1 ✗ | 41 Over 40 |
| Dec 3, 2006 W13 | @ NO | SF 10–34 | +7 ✗ | 44 Under 45 |
| Sep 19, 2004 W2 | @ NO | SF 27–30 | +7.5 ✓ | 57 Over 42 |
| Oct 20, 2002 W7 | @ NO | SF 27–35 | +1.5 ✗ | 62 Over 48.5 |
| Jan 6, 2002 W17 | @ NO | SF 38–0 | −2.5 ✓ | 38 Under 46.5 |
| Nov 11, 2001 W9 | @ SF | SF 28–27 | −3 ✗ | 55 Over 45 |
| Dec 10, 2000 W15 | @ SF | SF 27–31 | −3 ✗ | 58 Over 47.5 |
| Nov 5, 2000 W10 | @ NO | SF 15–31 | +5.5 ✗ | 46 Under 48 |
| Nov 14, 1999 W10 | @ NO | SF 6–24 | −1 ✗ | 30 Under 38.5 |
| Sep 19, 1999 W2 | @ SF | SF 28–21 | −11 ✗ | 49 Over 42.5 |