NFL Game Research · MachProp

49ers 4–2 straight up · 5–1 against the spread · overs 2–4 · 6 meetings

SF 30–10
Nov 21, 2021 · W11 · @ JAX
−6.5 ✓
Under 45
SF 44–33
Dec 24, 2017 · W16 · @ SF
+4 ✓
Over 43
SF 42–10
Oct 27, 2013 · W8 · Neutral
−16 ✓
Over 40
SF 20–3
Nov 29, 2009 · W12 · @ SF
−3 ✓
Under 42.5
SF 9–10
Dec 18, 2005 · W15 · @ JAX
+14.5 ✓
Under 39.5
SF 3–41
Sep 12, 1999 · W1 · @ JAX
+5.5 ✗
Under 49

Date	Venue	Score	Spread	Total
Nov 21, 2021 W11	@ JAX	SF 30–10	−6.5 ✓	40 Under 45
Dec 24, 2017 W16	@ SF	SF 44–33	+4 ✓	77 Over 43
Oct 27, 2013 W8	Neutral	SF 42–10	−16 ✓	52 Over 40
Nov 29, 2009 W12	@ SF	SF 20–3	−3 ✓	23 Under 42.5
Dec 18, 2005 W15	@ JAX	SF 9–10	+14.5 ✓	19 Under 39.5
Sep 12, 1999 W1	@ JAX	SF 3–41	+5.5 ✗	44 Under 49