NFL Game Research · MachProp

49ers 1–5 straight up · 2–4 against the spread · overs 3–3 · 6 meetings

SF 18–30
Oct 24, 2021 · W7 · @ SF
−3.5 ✗
Over 41.5
SF 23–26
Oct 8, 2017 · W5 · @ IND
−1 ✗
Over 43.5
SF 7–27
Sep 22, 2013 · W3 · @ SF
−10.5 ✗
Under 45.5
SF 14–18
Nov 1, 2009 · W8 · @ IND
+13 ✓
Under 45
SF 3–28
Oct 9, 2005 · W5 · @ SF
+14 ✗
Under 47
SF 40–21
Nov 25, 2001 · W11 · @ IND
+2.5 ✓
Over 52.5

Date	Venue	Score	Spread	Total
Oct 24, 2021 W7	@ SF	SF 18–30	−3.5 ✗	48 Over 41.5
Oct 8, 2017 W5	@ IND	SF 23–26	−1 ✗	49 Over 43.5
Sep 22, 2013 W3	@ SF	SF 7–27	−10.5 ✗	34 Under 45.5
Nov 1, 2009 W8	@ IND	SF 14–18	+13 ✓	32 Under 45
Oct 9, 2005 W5	@ SF	SF 3–28	+14 ✗	31 Under 47
Nov 25, 2001 W11	@ IND	SF 40–21	+2.5 ✓	61 Over 52.5