NFL Game Research · MachProp

49ers 3–3 straight up · 3–3 against the spread · overs 4–2 · 6 meetings

SF 24–34
Dec 7, 2020 · W13 · Neutral
−1.5 ✗
Over 48
SF 16–45
Oct 16, 2016 · W6 · @ BUF
+7.5 ✗
Over 44
SF 45–3
Oct 7, 2012 · W5 · @ SF
−10 ✓
Over 45.5
SF 10–3
Nov 30, 2008 · W13 · @ BUF
+6.5 ✓
Under 43
SF 7–41
Dec 26, 2004 · W16 · @ SF
+10 ✗
Over 41.5
SF 35–0
Dec 2, 2001 · W12 · @ SF
−8.5 ✓
Under 44.5

Date	Venue	Score	Spread	Total
Dec 7, 2020 W13	Neutral	SF 24–34	−1.5 ✗	58 Over 48
Oct 16, 2016 W6	@ BUF	SF 16–45	+7.5 ✗	61 Over 44
Oct 7, 2012 W5	@ SF	SF 45–3	−10 ✓	48 Over 45.5
Nov 30, 2008 W13	@ BUF	SF 10–3	+6.5 ✓	13 Under 43
Dec 26, 2004 W16	@ SF	SF 7–41	+10 ✗	48 Over 41.5
Dec 2, 2001 W12	@ SF	SF 35–0	−8.5 ✓	35 Under 44.5